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hierarchical clustering and heatmap viewer user-interface  (Zambon)

 
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    Structured Review

    Zambon hierarchical clustering and heatmap viewer user-interface
    A) De novo identified cell populations from the software ICGS are shown for each scRNA-Seq platform. The displayed heatmaps were produced by the MarkerFinder algorithm, downstream of the ICGS population predictions, with yellow indicating high relative gene expression and blue or black, low or no gene expression in the associated genes (rows). Prior established embryonic kidney marker genes corresponding to compartments are shown in panel C. Text to the left of each <t>heatmap</t> indicates the statistical enrichment of genes from the Drop-Seq ICGS analysis for the 16 identified populations (MarkerFinder) using the embedded gene-set enrichment analysis tool GO-Elite in <t>AltAnalyze.</t> B–C) t-SNE plot derived from the ICGS heatmaps in panel A, where each dot represents individual cells colored according to its B) ICGS cluster annotation or C) prior established population specific genes. CD: Collecting duct, UT: Ureteric Tip, LOH: Loop of Henle, RV: Renal vesicle, DCSB: Distal comma shaped body, Pod: podocyte, PT: Proximal Tubule, PA: Pre-tubular aggregate, CM: Cap mesenchyme, Endo: Endothelium, NZS: Nephrogenic Stroma, CS: Cortical Stroma.
    Hierarchical Clustering And Heatmap Viewer User Interface, supplied by Zambon, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hierarchical+clustering+and+heatmap+viewer+user-interface/hierarchical+clustering+and+heatmap+viewer+user+interface/pmc05930237-74-20-31
    Average 90 stars, based on 1 article reviews
    hierarchical clustering and heatmap viewer user-interface - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf"

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf

    Journal: Developmental biology

    doi: 10.1016/j.ydbio.2017.11.006

    A) De novo identified cell populations from the software ICGS are shown for each scRNA-Seq platform. The displayed heatmaps were produced by the MarkerFinder algorithm, downstream of the ICGS population predictions, with yellow indicating high relative gene expression and blue or black, low or no gene expression in the associated genes (rows). Prior established embryonic kidney marker genes corresponding to compartments are shown in panel C. Text to the left of each heatmap indicates the statistical enrichment of genes from the Drop-Seq ICGS analysis for the 16 identified populations (MarkerFinder) using the embedded gene-set enrichment analysis tool GO-Elite in AltAnalyze. B–C) t-SNE plot derived from the ICGS heatmaps in panel A, where each dot represents individual cells colored according to its B) ICGS cluster annotation or C) prior established population specific genes. CD: Collecting duct, UT: Ureteric Tip, LOH: Loop of Henle, RV: Renal vesicle, DCSB: Distal comma shaped body, Pod: podocyte, PT: Proximal Tubule, PA: Pre-tubular aggregate, CM: Cap mesenchyme, Endo: Endothelium, NZS: Nephrogenic Stroma, CS: Cortical Stroma.
    Figure Legend Snippet: A) De novo identified cell populations from the software ICGS are shown for each scRNA-Seq platform. The displayed heatmaps were produced by the MarkerFinder algorithm, downstream of the ICGS population predictions, with yellow indicating high relative gene expression and blue or black, low or no gene expression in the associated genes (rows). Prior established embryonic kidney marker genes corresponding to compartments are shown in panel C. Text to the left of each heatmap indicates the statistical enrichment of genes from the Drop-Seq ICGS analysis for the 16 identified populations (MarkerFinder) using the embedded gene-set enrichment analysis tool GO-Elite in AltAnalyze. B–C) t-SNE plot derived from the ICGS heatmaps in panel A, where each dot represents individual cells colored according to its B) ICGS cluster annotation or C) prior established population specific genes. CD: Collecting duct, UT: Ureteric Tip, LOH: Loop of Henle, RV: Renal vesicle, DCSB: Distal comma shaped body, Pod: podocyte, PT: Proximal Tubule, PA: Pre-tubular aggregate, CM: Cap mesenchyme, Endo: Endothelium, NZS: Nephrogenic Stroma, CS: Cortical Stroma.

    Techniques Used: Software, Produced, Gene Expression, Marker, Derivative Assay

    Heatmap with representative cells from the CM: cap mesenchyme, PA: pretubular aggregate, DCSB: distal comma shaped body, MSSB: mid S-shaped body, PT: proximal tubule, LOH: loop of Henle, and Pod: Podocyte clusters from Drop-seq, Chromium 10X Genomics, and Fluidigm 800-cell. The early progenitor CM cells show stochastic expression of markers of multiple lineages. The MSSB cells are more committed and show elevated expression of proximal tubule associated genes and reduced expression of podocyte marker genes.
    Figure Legend Snippet: Heatmap with representative cells from the CM: cap mesenchyme, PA: pretubular aggregate, DCSB: distal comma shaped body, MSSB: mid S-shaped body, PT: proximal tubule, LOH: loop of Henle, and Pod: Podocyte clusters from Drop-seq, Chromium 10X Genomics, and Fluidigm 800-cell. The early progenitor CM cells show stochastic expression of markers of multiple lineages. The MSSB cells are more committed and show elevated expression of proximal tubule associated genes and reduced expression of podocyte marker genes.

    Techniques Used: Expressing, Marker

    Related Articles

    Software:

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf
    Article Snippet: Gene set enrichment analysis of ToppGene defined GUDMAP genes was performed using the GO-Elite option in the hierarchical clustering and heatmap viewer user-interface in AltAnalyze ( Chen et al., 2009 ; Zambon et al., 2012 ).

    Produced:

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf
    Article Snippet: Gene set enrichment analysis of ToppGene defined GUDMAP genes was performed using the GO-Elite option in the hierarchical clustering and heatmap viewer user-interface in AltAnalyze ( Chen et al., 2009 ; Zambon et al., 2012 ).

    Gene Expression:

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf
    Article Snippet: Gene set enrichment analysis of ToppGene defined GUDMAP genes was performed using the GO-Elite option in the hierarchical clustering and heatmap viewer user-interface in AltAnalyze ( Chen et al., 2009 ; Zambon et al., 2012 ).

    Marker:

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf
    Article Snippet: Gene set enrichment analysis of ToppGene defined GUDMAP genes was performed using the GO-Elite option in the hierarchical clustering and heatmap viewer user-interface in AltAnalyze ( Chen et al., 2009 ; Zambon et al., 2012 ).

    Derivative Assay:

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf
    Article Snippet: Gene set enrichment analysis of ToppGene defined GUDMAP genes was performed using the GO-Elite option in the hierarchical clustering and heatmap viewer user-interface in AltAnalyze ( Chen et al., 2009 ; Zambon et al., 2012 ).

    Expressing:

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf
    Article Snippet: Gene set enrichment analysis of ToppGene defined GUDMAP genes was performed using the GO-Elite option in the hierarchical clustering and heatmap viewer user-interface in AltAnalyze ( Chen et al., 2009 ; Zambon et al., 2012 ).



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    Zambon hierarchical clustering and heatmap viewer user-interface
    A) De novo identified cell populations from the software ICGS are shown for each scRNA-Seq platform. The displayed heatmaps were produced by the MarkerFinder algorithm, downstream of the ICGS population predictions, with yellow indicating high relative gene expression and blue or black, low or no gene expression in the associated genes (rows). Prior established embryonic kidney marker genes corresponding to compartments are shown in panel C. Text to the left of each <t>heatmap</t> indicates the statistical enrichment of genes from the Drop-Seq ICGS analysis for the 16 identified populations (MarkerFinder) using the embedded gene-set enrichment analysis tool GO-Elite in <t>AltAnalyze.</t> B–C) t-SNE plot derived from the ICGS heatmaps in panel A, where each dot represents individual cells colored according to its B) ICGS cluster annotation or C) prior established population specific genes. CD: Collecting duct, UT: Ureteric Tip, LOH: Loop of Henle, RV: Renal vesicle, DCSB: Distal comma shaped body, Pod: podocyte, PT: Proximal Tubule, PA: Pre-tubular aggregate, CM: Cap mesenchyme, Endo: Endothelium, NZS: Nephrogenic Stroma, CS: Cortical Stroma.
    Hierarchical Clustering And Heatmap Viewer User Interface, supplied by Zambon, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hierarchical+clustering+and+heatmap+viewer+user-interface/hierarchical+clustering+and+heatmap+viewer+user+interface/pmc05930237-74-20-31
    Average 90 stars, based on 1 article reviews
    hierarchical clustering and heatmap viewer user-interface - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    Image Search Results


    A) De novo identified cell populations from the software ICGS are shown for each scRNA-Seq platform. The displayed heatmaps were produced by the MarkerFinder algorithm, downstream of the ICGS population predictions, with yellow indicating high relative gene expression and blue or black, low or no gene expression in the associated genes (rows). Prior established embryonic kidney marker genes corresponding to compartments are shown in panel C. Text to the left of each heatmap indicates the statistical enrichment of genes from the Drop-Seq ICGS analysis for the 16 identified populations (MarkerFinder) using the embedded gene-set enrichment analysis tool GO-Elite in AltAnalyze. B–C) t-SNE plot derived from the ICGS heatmaps in panel A, where each dot represents individual cells colored according to its B) ICGS cluster annotation or C) prior established population specific genes. CD: Collecting duct, UT: Ureteric Tip, LOH: Loop of Henle, RV: Renal vesicle, DCSB: Distal comma shaped body, Pod: podocyte, PT: Proximal Tubule, PA: Pre-tubular aggregate, CM: Cap mesenchyme, Endo: Endothelium, NZS: Nephrogenic Stroma, CS: Cortical Stroma.

    Journal: Developmental biology

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf

    doi: 10.1016/j.ydbio.2017.11.006

    Figure Lengend Snippet: A) De novo identified cell populations from the software ICGS are shown for each scRNA-Seq platform. The displayed heatmaps were produced by the MarkerFinder algorithm, downstream of the ICGS population predictions, with yellow indicating high relative gene expression and blue or black, low or no gene expression in the associated genes (rows). Prior established embryonic kidney marker genes corresponding to compartments are shown in panel C. Text to the left of each heatmap indicates the statistical enrichment of genes from the Drop-Seq ICGS analysis for the 16 identified populations (MarkerFinder) using the embedded gene-set enrichment analysis tool GO-Elite in AltAnalyze. B–C) t-SNE plot derived from the ICGS heatmaps in panel A, where each dot represents individual cells colored according to its B) ICGS cluster annotation or C) prior established population specific genes. CD: Collecting duct, UT: Ureteric Tip, LOH: Loop of Henle, RV: Renal vesicle, DCSB: Distal comma shaped body, Pod: podocyte, PT: Proximal Tubule, PA: Pre-tubular aggregate, CM: Cap mesenchyme, Endo: Endothelium, NZS: Nephrogenic Stroma, CS: Cortical Stroma.

    Article Snippet: Gene set enrichment analysis of ToppGene defined GUDMAP genes was performed using the GO-Elite option in the hierarchical clustering and heatmap viewer user-interface in AltAnalyze ( Chen et al., 2009 ; Zambon et al., 2012 ).

    Techniques: Software, Produced, Gene Expression, Marker, Derivative Assay

    Heatmap with representative cells from the CM: cap mesenchyme, PA: pretubular aggregate, DCSB: distal comma shaped body, MSSB: mid S-shaped body, PT: proximal tubule, LOH: loop of Henle, and Pod: Podocyte clusters from Drop-seq, Chromium 10X Genomics, and Fluidigm 800-cell. The early progenitor CM cells show stochastic expression of markers of multiple lineages. The MSSB cells are more committed and show elevated expression of proximal tubule associated genes and reduced expression of podocyte marker genes.

    Journal: Developmental biology

    Article Title: Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf

    doi: 10.1016/j.ydbio.2017.11.006

    Figure Lengend Snippet: Heatmap with representative cells from the CM: cap mesenchyme, PA: pretubular aggregate, DCSB: distal comma shaped body, MSSB: mid S-shaped body, PT: proximal tubule, LOH: loop of Henle, and Pod: Podocyte clusters from Drop-seq, Chromium 10X Genomics, and Fluidigm 800-cell. The early progenitor CM cells show stochastic expression of markers of multiple lineages. The MSSB cells are more committed and show elevated expression of proximal tubule associated genes and reduced expression of podocyte marker genes.

    Article Snippet: Gene set enrichment analysis of ToppGene defined GUDMAP genes was performed using the GO-Elite option in the hierarchical clustering and heatmap viewer user-interface in AltAnalyze ( Chen et al., 2009 ; Zambon et al., 2012 ).

    Techniques: Expressing, Marker